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Incidence And Possible Causative Factors Journal

There are two tumors that are often mistaken for GISTs and specifically those known as: (1) Fibromatosis; and (2) leomysarcoma. (Rubic, Heinrich, and Corless, 2007) Findings in this study include that there apparently are genetic bases for development of gastrointestinal stromal tumor and that in the Chinese population that when comparing the U.S. And Hong Kong demonstrates that Hong Kong is comparable to the U.S. And lower than Finland. This is likely to be true for the entire Chinese population although this fact could not be confirmed in the present study. Findings in this study additional include the findings that the previous optimal treatment for GISTs is likely not to be the best method of treating this condition and indicating that further and additional research is required toward the necessity and needs of different treatment options that are evidence-based and found to be more effective in treating this condition.

Bibliography

Azhar, a.H.S., et al. (2009) a Retrospective Cohort Study of Gastrointestinal Stromal Tumours (Gist) in Husm for the Last 12 Years (1997 -- 2008) Department of Surgery, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. Online available at: http://www.colorectalmy.org/events/coloproctology_2009.pdf

Chan K, Chan C, Chow W, Kwan W, Kong C, Mak K, Leung M, Lau L.Gastrointestinal stromal tumors in a cohort of Chinese patients in Hong Kong.World J. Kastroenterol 2006 April;12(14):2223-2228

Corless, CL; Fletcher, JA, and Heinrich, MC (2004) Biology of gastrointestinal stromal tumors. Clin Oncol. 2004 Sep 15;22(18):3813-25.

Demetri GD, von Mehren M, Blanke CD, et al.: Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J. Med 347:472-480, 2002.

Heinrich MC, Corless CL, Duensing a, et al.: PDGFRA activating mutations in...

Science 299:708-710, 2003.
Mazur MT, Clark HB: Gastric stromal tumors. Reappraisal of histogenesis. Am J. Surg Pathol 7:507-519, 1983.

Medeiros F, Corless CL, Duensing a, et al.: Kit-negative gastrointestinal stromal tumors: Proof of concept and therapeutic implications. Am J. Surg Pathol 28:889-894, 2004.

Miettinen M, Furlong M, Sarlomo-Rikala M, et al.: Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: A clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J. Surg Pathol 25:1121-1133, 2001.

Miettinen M, Lasota J: Gastrointestinal stromal tumors: Pathology and prognosis at different sites. Semin Diagn Pathol 23:70-83, 2006.

Miettinen M, Sobin LH, Lasota J: Gastrointestinal stromal tumors of the stomach: A clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J. Surg Pathol 29:52-68, 2005.

Miettinen M, Virolainen M, Maarit SR: Gastrointestinal stromal tumors -- Value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J. Surg Pathol 19:207-216, 1995[Medline]

Mikhael AI, Bacchi CE, Zarbo RJ, et al.: CD34 expression in stromal tumors of the gastrointestinal tract. Appl Immunohistochem 2:89-93, 1994

Rubin BP, Heinrich MC, Corless CL: Gastrointestinal stromal tumour. Lancet 369:1731-1741, 2007.

Tzen, Chi-Yuan (2007) Incidence of Gastrointestinal Stromal Tumor: A Retrospective Study Based on Immunohistochemical and Mutational Analyses. Digestive Diseases and Sciences. 26 Jan 2007. vol. 52, No. 3.

Zhou, Weixun; Zeng, xuan; and Liu, Tonghua (2009) Aberrations of Chromosome 13q in Gastrointestinal Stromal Tumors: Analysis of 91 Cases by Fluorescence in Situ Hybridization…

Sources used in this document:
Bibliography

Azhar, a.H.S., et al. (2009) a Retrospective Cohort Study of Gastrointestinal Stromal Tumours (Gist) in Husm for the Last 12 Years (1997 -- 2008) Department of Surgery, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan, Malaysia. Online available at: http://www.colorectalmy.org/events/coloproctology_2009.pdf

Chan K, Chan C, Chow W, Kwan W, Kong C, Mak K, Leung M, Lau L.Gastrointestinal stromal tumors in a cohort of Chinese patients in Hong Kong.World J. Kastroenterol 2006 April;12(14):2223-2228

Corless, CL; Fletcher, JA, and Heinrich, MC (2004) Biology of gastrointestinal stromal tumors. Clin Oncol. 2004 Sep 15;22(18):3813-25.

Demetri GD, von Mehren M, Blanke CD, et al.: Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J. Med 347:472-480, 2002.
Zhou, Weixun; Zeng, xuan; and Liu, Tonghua (2009) Aberrations of Chromosome 13q in Gastrointestinal Stromal Tumors: Analysis of 91 Cases by Fluorescence in Situ Hybridization (FISH)Diagnostic Molecular Pathology: June 2009 - Volume 18 - Issue 2 - pp 72-80. Online available at: http://journals.lww.com/molecularpathology/Abstract/2009/06000/Aberrations_of_Chromosome_13q_in_Gastrointestinal.3.aspx
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